1. Structure
  2. Life Sciences
  3. Biomedical Imaging
  4. Foundation
  5. Key Concepts
  6. Reads
  • Home
  • What is TileDB?
  • Get Started
  • Explore Content
  • Accounts
    • Individual Accounts
      • Apply for the Free Tier
      • Profile
        • Overview
        • Cloud Credentials
        • Storage Paths
        • REST API Tokens
        • Credits
    • Organization Admins
      • Create an Organization
      • Profile
        • Overview
        • Members
        • Cloud Credentials
        • Storage Paths
        • Billing
      • API Tokens
    • Organization Members
      • Organization Invitations
      • Profile
        • Overview
        • Members
        • Cloud Credentials
        • Storage Paths
        • Billing
      • API Tokens
  • Catalog
    • Introduction
    • Data
      • Arrays
      • Tables
      • Single-Cell (SOMA)
      • Genomics (VCF)
      • Biomedical Imaging
      • Vector Search
      • Files
    • Code
      • Notebooks
      • Dashboards
      • User-Defined Functions
      • Task Graphs
      • ML Models
    • Groups
    • Marketplace
    • Search
  • Collaborate
    • Introduction
    • Organizations
    • Access Control
      • Introduction
      • Share Assets
      • Asset Permissions
      • Public Assets
    • Logging
    • Marketplace
  • Analyze
    • Introduction
    • Slice Data
    • Multi-Region Redirection
    • Notebooks
      • Launch a Notebook
      • Usage
      • Widgets
      • Notebook Image Dependencies
    • Dashboards
      • Dashboards
      • Streamlit
    • Preview
    • User-Defined Functions
    • Task Graphs
    • Serverless SQL
    • Monitor
      • Task Log
      • Task Graph Log
  • Scale
    • Introduction
    • Task Graphs
    • API Usage
  • Structure
    • Why Structure Is Important
    • Arrays
      • Introduction
      • Quickstart
      • Foundation
        • Array Data Model
        • Key Concepts
          • Storage
            • Arrays
            • Dimensions
            • Attributes
            • Cells
            • Domain
            • Tiles
            • Data Layout
            • Compression
            • Encryption
            • Tile Filters
            • Array Schema
            • Schema Evolution
            • Fragments
            • Fragment Metadata
            • Commits
            • Indexing
            • Array Metadata
            • Datetimes
            • Groups
            • Object Stores
          • Compute
            • Writes
            • Deletions
            • Consolidation
            • Vacuuming
            • Time Traveling
            • Reads
            • Query Conditions
            • Aggregates
            • User-Defined Functions
            • Distributed Compute
            • Concurrency
            • Parallelism
        • Storage Format Spec
      • Tutorials
        • Basics
          • Basic Dense Array
          • Basic Sparse Array
          • Array Metadata
          • Compression
          • Encryption
          • Data Layout
          • Tile Filters
          • Datetimes
          • Multiple Attributes
          • Variable-Length Attributes
          • String Dimensions
          • Nullable Attributes
          • Multi-Range Reads
          • Query Conditions
          • Aggregates
          • Deletions
          • Catching Errors
          • Configuration
          • Basic S3 Example
          • Basic TileDB Cloud
          • fromDataFrame
          • Palmer Penguins
        • Advanced
          • Schema Evolution
          • Advanced Writes
            • Write at a Timestamp
            • Get Fragment Info
            • Consolidation
              • Fragments
              • Fragment List
              • Consolidation Plan
              • Commits
              • Fragment Metadata
              • Array Metadata
            • Vacuuming
              • Fragments
              • Commits
              • Fragment Metadata
              • Array Metadata
          • Advanced Reads
            • Get Fragment Info
            • Time Traveling
              • Introduction
              • Fragments
              • Array Metadata
              • Schema Evolution
          • Array Upgrade
          • Backends
            • Amazon S3
            • Azure Blob Storage
            • Google Cloud Storage
            • MinIO
            • Lustre
          • Virtual Filesystem
          • User-Defined Functions
          • Distributed Compute
          • Result Estimation
          • Incomplete Queries
        • Management
          • Array Schema
          • Groups
          • Object Management
        • Performance
          • Summary of Factors
          • Dense vs. Sparse
          • Dimensions vs. Attributes
          • Compression
          • Tiling and Data Layout
          • Tuning Writes
          • Tuning Reads
      • API Reference
    • Tables
      • Introduction
      • Quickstart
      • Foundation
        • Data Model
        • Key Concepts
          • Indexes
          • Columnar Storage
          • Compression
          • Data Manipulation
          • Optimize Tables
          • ACID
          • Serverless SQL
          • SQL Connectors
          • Dataframes
          • CSV Ingestion
      • Tutorials
        • Basics
          • Ingestion with SQL
          • CSV Ingestion
          • Basic S3 Example
          • Running Locally
        • Advanced
          • Scalable Ingestion
          • Scalable Queries
      • API Reference
    • AI & ML
      • Vector Search
        • Introduction
        • Quickstart
        • Foundation
          • Data Model
          • Key Concepts
            • Vector Search
            • Vector Databases
            • Algorithms
            • Distance Metrics
            • Updates
            • Deployment Methods
            • Architecture
            • Distributed Compute
          • Storage Format Spec
        • Tutorials
          • Basics
            • Ingestion & Querying
            • Updates
            • Deletions
            • Basic S3 Example
            • Running Locally
          • Advanced
            • Versioning
            • Time Traveling
            • Consolidation
            • Distributed Compute
            • RAG LLM
            • LLM Memory
            • File Search
            • Image Search
            • Protein Search
          • Performance
        • API Reference
      • ML Models
        • Introduction
        • Quickstart
        • Foundation
          • Basics
          • Storage
          • Cloud Execution
          • Why TileDB for Machine Learning
        • Tutorials
          • Ingestion
            • Data Ingestion
              • Dense Datasets
              • Sparse Datasets
            • ML Model Ingestion
          • Management
            • Array Schema
            • Machine Learning: Groups
            • Time Traveling
    • Life Sciences
      • Single-cell
        • Introduction
        • Quickstart
        • Foundation
          • Data Model
          • Key Concepts
            • Data Structures
            • Use of Apache Arrow
            • Join IDs
            • State Management
            • TileDB Cloud URIs
          • SOMA API Specification
        • Tutorials
          • Data Ingestion
          • Bulk Ingestion Tutorial
          • Data Access
          • Distributed Compute
          • Basic S3 Example
          • Multi-Experiment Queries
          • Appending Data to a SOMA Experiment
          • Add New Measurements
          • SQL Queries
          • Running Locally
          • Shapes in TileDB-SOMA
          • Drug Discovery App
        • Spatial
          • Introduction
          • Foundation
            • Spatial Data Model
            • Data Structures
          • Tutorials
            • Spatial Data Ingestion
            • Access Spatial Data
            • Manage Coordinate Spaces
        • API Reference
      • Population Genomics
        • Introduction
        • Quickstart
        • Foundation
          • Data Model
          • Key Concepts
            • The N+1 Problem
            • Architecture
            • Arrays
            • Ingestion
            • Reads
            • Variant Statistics
            • Annotations
            • User-Defined Functions
            • Tables and SQL
            • Distributed Compute
          • Storage Format Spec
        • Tutorials
          • Basics
            • Basic Ingestion
            • Basic Queries
            • Export to VCF
            • Add New Samples
            • Deleting Samples
            • Basic S3 Example
            • Basic TileDB Cloud
          • Advanced
            • Scalable Ingestion
            • Scalable Queries
            • Query Transforms
            • Handling Large Queries
            • Annotations
              • Finding Annotations
              • Embedded Annotations
              • External Annotations
              • Annotation VCFs
              • Ingesting Annotations
            • Variant Statistics
            • Tables and SQL
            • User-Defined Functions
            • Sample Metadata
            • Split VCF
          • Performance
        • API Reference
          • Command Line Interface
          • Python API
          • Cloud API
      • Biomedical Imaging
        • Introduction
        • Foundation
          • Data Model
          • Key Concepts
            • Arrays
            • Ingestion
            • Reads
            • User Defined Functions
          • Storage Format Spec
        • Quickstart
        • Tutorials
          • Basics
            • Ingestion
            • Read
              • OpenSlide
              • TileDB-Py
          • Advanced
            • Batched Ingestion
            • Chunked Ingestion
            • Machine Learning
              • PyTorch
            • Napari
    • Files
  • API Reference
  • Self-Hosting
    • Installation
    • Upgrades
    • Administrative Tasks
    • Image Customization
      • Customize User-Defined Function Images
      • AWS ECR Container Registry
      • Customize Jupyter Notebook Images
    • Single Sign-On
      • Configure Single Sign-On
      • OpenID Connect
      • Okta SCIM
      • Microsoft Entra
  • Glossary

On this page

  • Slice
  • Scale with performance
  1. Structure
  2. Life Sciences
  3. Biomedical Imaging
  4. Foundation
  5. Key Concepts
  6. Reads

Biomedical Imaging Reads

life sciences
biomedical imaging
foundation
reads
Key concepts for reading imaging data stored in a TileDB-BioImaging dataset.

This section covers the key concepts related to reading variant data from a TileDB-BioImaging dataset. Visit the Arrays Key Concepts: Reads section for more foundational information about reading TileDB arrays.

Slice

As described in the storage format spec, each TileDB-BioImaging group includes multiple data arrays, which hold the image data of the image’s multiple resolutions. TileDB-BioImaging offers a set of methods to read these arrays that are familiar to people working with whole-slide bioimaging data, since it wraps the OpenSlide API. For example, you can read a slice of the image at a specific resolution by specifying the following:

  • A location tuple giving the top-left pixel of the highest resolution reference frame.
  • A resolution level.
  • A region size tuple.

The array data model of TileDB is optimized to perform this type of slicing, which is a powerful feature for data exploration and discovery.

Visit the Basic Queries tutorial for examples of TileDB-BioImaging read queries.

You can slice an image stored as a TileDB-BioImaging dataset by either using the TileDB-Py API for groups and arrays or the dedicated TileDBOpenSlide API offered in TileDB-BioImaging. Both APIs are covered in the following tutorials:

  • TileDB-Py API
  • OpenSlide API

Scale with performance

For TileDB-BioImaging datasets with multiple resolution levels, it is more efficient to slice image data by using the distributed compute architecture of TileDB. Partitioning and distributing a read query across multiple compute nodes has these advantages:

  • Each query accesses a subset of the total data, reducing the required compute resources (CPU and memory) and the query latency.
  • The queries run in parallel, taking advantage of independent compute resources and reducing the total query latency.

TileDB offers full automation of scalable reads.

Ingestion
User Defined Functions